Mythos 5.1
Mythos 5.1 is an Anthropic frontier model included in the Life Sciences Verification Program (LSVP), which provides verified life-science teams access with modified safeguards designed to permit biology-related workflows. The LSVP is a beta program for teams and institutions accessible via Anthropic’s consoles and API, with separate Standard Use and High-risk Use grants controlling the scope of allowed activities.
What it does
Project Glasswing participants can use it for AI tasks requiring a long context window and adaptive thinking.
- Availability
- For Project Glasswing participants
- Pricing model
- $10 / $50 USD per MTok; cache reads $0.25 USD per million tokens
- Deployment
- hosted
- Privacy
- Requires 30-day data retention; not available under zero data retention unless expressly authorized by Anthropic
- Licence
- Not established
Capability
Modality
Access
Deployment
Pricing
Target user
Evidence
10 claims- Standard Use grants enable the majority of biology research and development workflows on Mythos 5.1 that are blocked in generally available models.
- High-risk Use grants can remove safeguards that block life-sciences requests, but are limited for Mythos at launch and require additional vetting. [1]
We are working with the US government to make high-risk grants more broadly available for Claude Mythos, but at the time of this launch they will remain limited to a small set of entities with additional vetting.
Anthropic. Quoted text is outside CC BY 4.0 and keeps its original rights. - Mythos 5.1 is accessible to verified organizations through Anthropic’s first-party console (API usage) and Claude for Enterprise and Team plans under the LSVP beta.
- LSVP requires retention of data associated with flagged activity for 30 days and that retained data cannot be used for model training or accessed by Anthropic’s life sciences research teams.
- LSVP access to Mythos 5.1 is provided on Anthropic’s hosted surfaces (Claude.ai, Claude Science, Claude Code, and API).
- Claude Mythos 5.1 is for Project Glasswing participants. [2]
We've launched Claude Fable 5.1 ( claude-fable-5-1 ), the successor to Claude Fable 5 for long-running agentic coding, knowledge work, and research, alongside Claude Mythos 5.1 ( claude-mythos-5-1 ) for Project Glasswing participants.
Anthropic. Quoted text is outside CC BY 4.0 and keeps its original rights. - Both models support a 1M token context window by default and 128k max output tokens. [2]
Both models support a 1M token context window by default, 128k max output tokens, and always-on adaptive thinking , at $10 / $50 USD per MTok, the same as Claude Fable 5, with cache reads cut to $0.25 USD per MTok.
Anthropic. Quoted text is outside CC BY 4.0 and keeps its original rights. - Claude Mythos 5.1 supports always-on adaptive thinking. [2]
We've launched Claude Fable 5.1 ( claude-fable-5-1 ), the successor to Claude Fable 5 for long-running agentic coding, knowledge work, and research, alongside Claude Mythos 5.1 ( claude-mythos-5-1 ) for Project Glasswing participants.
Anthropic. Quoted text is outside CC BY 4.0 and keeps its original rights. - Prompt cache reads on Claude Mythos 5.1 cost $0.25 USD per million tokens. [2]
Prompt cache reads on Claude Fable 5.1 and Claude Mythos 5.1 cost $0.25 USD per million tokens: 0.025x the base input price, compared with 0.1x on other models.
Anthropic. Quoted text is outside CC BY 4.0 and keeps its original rights. - Claude Mythos 5.1 requires 30-day data retention and isn't available under zero data retention unless expressly authorized by Anthropic. [2]
Like Claude Fable 5, both models require 30-day data retention and aren't available under zero data retention unless expressly authorized by Anthropic.
Anthropic. Quoted text is outside CC BY 4.0 and keeps its original rights.
Sources
2
1
AnthropicOwner-controlled
https://www.anthropic.com/news/life-sciences-verification-program
Retrieved 2026-10-27 01:40 UTC
Verified
2
AnthropicOwner-controlled
https://docs.claude.com/en/release-notes/overview#2026-09-01
Retrieved 2026-10-27 01:40 UTC
Verified
Versions
3| Version | Effective | Change | Changed fields | State |
|---|---|---|---|---|
| 3 | 2026-10-24 01:17 UTC | material change | capability, modality, access, pricing, availability, pricing model, privacy | Current |
| 2 | 2026-10-17 18:59 UTC | evidence update | score | Current |
| 1 | 2026-09-23 17:21 UTC | publication | None | Current |
Original catalog content is licensed under CC BY 4.0, attributed to wowsuchai. Source quotations and linked content keep their original rights.
