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AnthropicModel

Mythos 5.1

Mythos 5.1 is an Anthropic frontier model included in the Life Sciences Verification Program (LSVP), which provides verified life-science teams access with modified safeguards designed to permit biology-related workflows. The LSVP is a beta program for teams and institutions accessible via Anthropic’s consoles and API, with separate Standard Use and High-risk Use grants controlling the scope of allowed activities.

What it does

Project Glasswing participants can use it for AI tasks requiring a long context window and adaptive thinking.

Availability
For Project Glasswing participants
Pricing model
$10 / $50 USD per MTok; cache reads $0.25 USD per million tokens
Deployment
hosted
Privacy
Requires 30-day data retention; not available under zero data retention unless expressly authorized by Anthropic
Licence
Not established
Capability
agentsanalysis
Modality
textcode
Access
API
Deployment
hosted
Pricing
usage-based
Target user
researcherdeveloperenterprise

Evidence

10 claims
  • Standard Use grants enable the majority of biology research and development workflows on Mythos 5.1 that are blocked in generally available models.
  • High-risk Use grants can remove safeguards that block life-sciences requests, but are limited for Mythos at launch and require additional vetting. [1]
    We are working with the US government to make high-risk grants more broadly available for Claude Mythos, but at the time of this launch they will remain limited to a small set of entities with additional vetting.
    Anthropic. Quoted text is outside CC BY 4.0 and keeps its original rights.
  • Mythos 5.1 is accessible to verified organizations through Anthropic’s first-party console (API usage) and Claude for Enterprise and Team plans under the LSVP beta.
  • LSVP requires retention of data associated with flagged activity for 30 days and that retained data cannot be used for model training or accessed by Anthropic’s life sciences research teams.
  • LSVP access to Mythos 5.1 is provided on Anthropic’s hosted surfaces (Claude.ai, Claude Science, Claude Code, and API).
  • Claude Mythos 5.1 is for Project Glasswing participants. [2]
    We've launched Claude Fable 5.1 ( claude-fable-5-1 ), the successor to Claude Fable 5 for long-running agentic coding, knowledge work, and research, alongside Claude Mythos 5.1 ( claude-mythos-5-1 ) for Project Glasswing participants.
    Anthropic. Quoted text is outside CC BY 4.0 and keeps its original rights.
  • Both models support a 1M token context window by default and 128k max output tokens. [2]
    Both models support a 1M token context window by default, 128k max output tokens, and always-on adaptive thinking , at $10 / $50 USD per MTok, the same as Claude Fable 5, with cache reads cut to $0.25 USD per MTok.
    Anthropic. Quoted text is outside CC BY 4.0 and keeps its original rights.
  • Claude Mythos 5.1 supports always-on adaptive thinking. [2]
    We've launched Claude Fable 5.1 ( claude-fable-5-1 ), the successor to Claude Fable 5 for long-running agentic coding, knowledge work, and research, alongside Claude Mythos 5.1 ( claude-mythos-5-1 ) for Project Glasswing participants.
    Anthropic. Quoted text is outside CC BY 4.0 and keeps its original rights.
  • Prompt cache reads on Claude Mythos 5.1 cost $0.25 USD per million tokens. [2]
    Prompt cache reads on Claude Fable 5.1 and Claude Mythos 5.1 cost $0.25 USD per million tokens: 0.025x the base input price, compared with 0.1x on other models.
    Anthropic. Quoted text is outside CC BY 4.0 and keeps its original rights.
  • Claude Mythos 5.1 requires 30-day data retention and isn't available under zero data retention unless expressly authorized by Anthropic. [2]
    Like Claude Fable 5, both models require 30-day data retention and aren't available under zero data retention unless expressly authorized by Anthropic.
    Anthropic. Quoted text is outside CC BY 4.0 and keeps its original rights.

Sources

2
1
AnthropicOwner-controlled
https://www.anthropic.com/news/life-sciences-verification-program Retrieved 2026-10-27 01:40 UTC
Verified
2
AnthropicOwner-controlled
https://docs.claude.com/en/release-notes/overview#2026-09-01 Retrieved 2026-10-27 01:40 UTC
Verified

Versions

3
VersionEffectiveChangeChanged fieldsState
32026-10-24 01:17 UTCmaterial changecapability, modality, access, pricing, availability, pricing model, privacyCurrent
22026-10-17 18:59 UTCevidence updatescoreCurrent
12026-09-23 17:21 UTCpublicationNoneCurrent

Open in the catalog

Original catalog content is licensed under CC BY 4.0, attributed to wowsuchai. Source quotations and linked content keep their original rights.